Items tagged with Prevention
TB prevention trial fails (post)
Preventive tuberculosis therapy had no lasting effect on TB incidence among South African gold miners -- a group hard-hit by the disease, researchers reported.
The Centers for Disease Control and Prevention is recognizing next week’s World TB Day with a report documenting continued progress against tuberculosis at in the United States, along with an troubling trend. The progress: the 3.0 cases per 100,000 people reported in 2013 (9,588 new cases) represents a more than 4 percent drop from 2012. The troubling part is that progress still is not shared equally: while incidence also dropped among foreign-born people in the United States, it is not dropping as fast as it is for those born in the United States. That means that the proportion of the impact of tuberculosis on people born outside of the United States is increasing, with their rate of the disease about thirteen times that of people born here. With TB elimination defined as less than one case per 100,000 people, the goal of eliminating tuberculosis in the United States remains unreached.
TB in the United States (post)
In advance of World TB Day, the U.S. Centers for Disease Control and Prevention (CDC) released 2 new studies, one summarizing the latest national TB surveillance data for 2013, the second looking at the toll of drug-resistant TB in the U.S.
Taking cotrimoxazole decreased tuberculosis incidence 13% to 30% in HIV-positive adults in Switzerland, depending on whether they were already taking antiretrovirals.
Fewer people will contract tuberculosis (TB) this year than last. That is good news, and enough to meet the United Nations Millennium Development Goal that called “to halt and begin to reverse the incidence” of TB. But the pace of progress is too slow. Some 8.6 million people contracted the disease in 2012, and 1.3 million died, including 320,000 people with HIV. As it stands, the world will miss the international target to eliminate TB by 2050. To meet that ambitious goal, we need to modernize the way in which we tackle the disease. This means that fundamental research must play a bigger part in nurturing the development of diagnostics, medicines and vaccines.
Scientists studying the role of room ventilation in tuberculosis transmission found that students in Cape Town, South Africa, spend almost 60 percent of their day in poorly ventilated rooms, at risk of transmission, according to results published May 7, 2014, in the open access journal PLOS ONE by Eugene Richardson from Stanford University School of Medicine and colleagues. The researchers propose an increase in low-cost, WHO-compliant natural ventilation to facilitate healthy indoor environments and reduce risks.
Active TB case finding and isoniazid (INH) preventive therapy (IPT) are feasible among pregnant women in maternal and child health clinics in Lesotho, a country with high HIV and TB prevalence, according to results of an 800-woman study.
PHILADELPHIA, PA—The use of isoniazid as preventive therapy among HIV-infected patients receiving highly active antiretroviral therapy (HAART) is associated with significantly lower tuberculosis incidence, reported Bethel Shiferaw, MD, MPH, from Nassau University Medical Center, East Meadow, at IDWeek 2014.
The discovery opens up new routes to treat and prevent the infectious disease which kills 1.5 million people a year.
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