Items tagged with Diagnostics
AI method shows promise for detecting active TB on X-ray (post)
January 26, 2023 -- Researchers in India have developed a new artificial intelligence (AI) model for detecting active tuberculosis on chest x-rays, and they suggest that the approach offers significant potential for real-world applications in locations with limited resources.
Diagnostic care for TB significantly limited among HIV-positive inpatients (post)
There was a significant gap in TB diagnostic care both before and during the COVID-19 pandemic among hospitalized patients with advanced HIV infection.
Invitation for public comments on draft WHO tuberculosis target product profiles (post)
The World Health Organization (WHO) invites all stakeholders to comment by 9 March 2023 on the latest drafts of the target regimen profiles (TRPs) for TB treatment and the target product profiles (TPPs) for tests for TB treatment monitoring and optimization, by means of online feedback forms.
Latest Union guide for diagnosis and management of TB in children and adolescents launches (post)
9 February 2023: Today, the fourth edition of The Union’s desk guide for diagnosis and management of tuberculosis (TB) in children and adolescents has been published.
CROI 2023 TB research round up (post)
Treatment Action Group (TAG) released an overview of TB research data reported at the 30th Conference on Retroviruses and Opportunistic Infections (CROI 2023) held on 19-22 February 2023 in Seattle, Washington, USA. Highlights include the much-anticipated results of the SimpliciTB trial; additional analyses of the two-month TB treatment regimen studied in the TRUNCATE-TB trial; and the first clinical trial data on sutezolid since 2012.
Roche joins forces with CDC to strengthen laboratory systems in the fight against the HIV and TB epidemics (post)
Roche announced the expansion of its collaboration with the U.S. Centers for Disease Control and Prevention (CDC) to strengthen laboratory capabilities in countries greatly affected by the HIV and TB epidemics. Through the implementation of a public-private partnership, named “Lab Networks for Health,” Roche and the CDC will seek to improve HIV and TB prevention, detection and treatment outcomes in select countries of Africa, Eastern Europe, Central Asia and the Western Hemisphere (e.g., Latin America, Central America and Caribbean regions).
Wayne State researchers develop new technology to easily detect active TB (post)
DETROIT, March 13, 2023 – A team of faculty from Wayne State University has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection antibodies. Their work, “Discovery of Novel Transketolase Epitopes and the Development of IgG-Based Tuberculosis Serodiagnostics,” was published in a recent edition of Microbiology Spectrum, a journal published by the American Society for Microbiology. The team is led by Lobelia Samavati, M.D., professor in the Center for Molecular Medicine and Genetics in the School of Medicine. Samavati was joined by Jaya Talreja, Ph.D, and Changya Peng, research scientists in Wayne State’s Department of Internal Medicine.
Global Fund, USAID and Stop TB Partnership's new collaboration with Molbio Diagnostics will increase access to rapid molecular tests for TB (post)
GENEVA/WASHINGTON, 09 March 2023 – The Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund), the United States Agency for International Development (USAID) and the Stop TB Partnership announced a new collaboration today with Molbio Diagnostics that significantly reduces the price of the Truenat® MTB and MTB Plus tests, including a supply of MTB-RIF Dx tests for subsequent testing for rifampicin resistance, and ensures timely service and maintenance of diagnostic instruments. This collaboration will expand equitable access to quality rapid testing to underserved populations across all countries supported by the Global Fund, USAID and the Stop TB Partnership.
Feasible and effective new community-based diagnostic technique for TB (post)
Results from a community-based trial of a new package for diagnosing TB emphasise the importance of moving towards an active case finding approach for the disease.
International consensus highlights the importance of molecular testing for antibiotic resistance in TB management (post)
A multidisciplinary group of tuberculosis experts from the TBnet and RESIST-TB networks have reached a consensus on key issues related to the molecular prediction of Mycobacterium tuberculosis antibiotic sensitivity or resistance and its clinical implications. The consensus document provides guidance for the design of therapeutic regimens and the optimization of treatments, and is intended to help clinicians manage tuberculosis patients. The paper, published in The Lancet Infectious Diseases and led by Dr José Domínguez from the Germans Trias i Pujol Research Institute (IGTP), is an update of a similar statement made in 2016. The publication presents a review of the current tools to rapidly identify resistance to drugs used in the treatment of tuberculosis.
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