Items tagged with Diagnostics

The story of rats fighting TB, landmines to save human life (post)

Dar es Salaam.They are mostly known for their destructive characteristics, and for that reason rats are generally hated.

Students’ rapid TB test could save lives (post)

Three McCormick School of Engineering students have developed an automated staining system using 3D printing technology that enables high-throughput sputum smear diagnostics for TB at the patient’s point of care (POC). The design, named POCAS TB and built during the biomedical engineering capstone BME 390-1-20: Biomedical Engineering Design course, recently earned the Design by Biomedical Undergraduate Teams (DEBUT) Challenge’s NIH Office of AIDS Research (OAR) Prize for HIV/AIDS.

New testing method could make TB diagnosis easier (post)

Tuberculosis can be tough to detect. Diagnosis usually requires coughing up a sputum sample from the lungs, which can be unpleasant, impractical, and even hazardous. But in a promising new study, a multinational team of researchers may have found another way to identify the bacterial disease.

Advancing the diagnosis of child TB: CXR image library (post)

The International Union Against Tuberculosis and Lung Disease released Diagnostic CXR Atlas for Tuberculosis in Children Image Library.

Illumina and GenoScreen partner to expand access to genomic testing for multidrug-resistant TB (post)

SAN DIEGO, Oct. 18, 2022 -- Illumina Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, and GenoScreen, an innovative genomics company, today announced a partnership to accelerate progress to end tuberculosis (TB) worldwide. The partnership will expand capabilities for countries most impacted by tuberculosis to more effectively detect and combat multidrug-resistant TB (MDR-TB). This alliance will enable global access to a package combining Illumina sequencing products and the GenoScreen Deeplex® Myc-TB assay, a targeted next-generation sequencing (NGS) based test for rapid and extensive detection of anti-TB drug resistance, to promptly inform treatment decision. This will help advance the World Health Organization's (WHO) strategy to end the global TB epidemic by 2035.

PBD Biotech raises further £2.4m for its breakthrough TB blood test (post)

Human tuberculosis is second only to Covid as the world’s most fatal infectious disease; although treatable, there remains a global unmet need to diagnose the disease at an earlier stage and to identify carriers that may develop the disease. To address these objectives, PBD Biotech has developed a rapid screening blood test that shows promise for identifying people with the disease as well as a subgroup with pre-clinical infection at higher risk of developing the disease, offering the potential to revolutionise management of TB. The company has raised follow-on funding of £2.4M to support further clinical trials.

Digital X-rays boosting TB diagnosis, assessment finds (post)

TB diagnosis usually starts with asking someone whether they have any of the classic symptoms of TB (coughing, fever, loss of weight, and drenching night sweats in adults). Traditionally, only people who have one or more of these symptoms are offered confirmatory molecular tests.

Chest X-ray aids in early diagnosis of children exposed to TB (post)

In children exposed to tuberculosis, chest radiography helped in detecting asymptomatic coprevalent TB and predicting incident TB after baseline, according to a study in American Journal of Respiratory and Critical Care Medicine.

Mylab launches first indigenous TB diagnostic kit in India (post)

Pune-based diagnostic kit manufacturer Mylab Discovery Solutions has launched India’s first indigenously developed Tuberculosis detection kit. The PathoDetect kit can also detect multiple drug resistance to Rifampicin and Isoniazid in a single test. TB is one of the biggest killers in India with 4.93 lakh deaths reported in 2020.

TB and COVID-19 lung lesions revealed by high-resolution three-dimensional imaging (post)

Gross anatomy reveals three-dimensional shapes of pathology at a large scale. Histology, in contrast, reveals the microscopic anatomy of biological structures. But that magnification comes at a cost — histology shows only two-dimensional shapes because it studies small, flat slices of stained tissue.

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