Smart medication container included in Stop TB Partnership's Global Drug Facility (GDF) product catalog.
12 November 2020 - Geneva, Switzerland, and The Hague, Netherlands –Stop TB Partnership’s Global Drug Facility (GDF) and the Unitaid-funded Adherence Support Coalition to End TB (ASCENT project) announce the inclusion of the first digital adherence technology (DAT) in the GDF’s product catalog: the Wisepill evriMED smart medication container. This marks a turning point in efforts to improve people-centered tuberculosis (TB) treatment.
The introduction of innovative technologies, such as the smart medication container, supports real-time self-administered treatment. Every time a TB-affected person opens the container to take his or her medicines, the embedded device automatically logs the daily dose. If the container is not opened for multiple days, it may mean some doses were missed. The healthcare provider will be notified and they can then work with the TB-affected person to develop a personalized treatment support plan designed to help him or her complete treatment.
Multiple barriers can prevent affected people from completing their treatment. This can be due to long and complicated treatment regimens that involve the daily intake of medicines over the course of six months to two years. Not completing a treatment course can result in relapse of the disease and increased resistance to TB medicines – meaning more complicated and expensive medicines and regimens may be needed to treat the affected person successfully.
DATs' advent is part of a shift towards people-centered care, enabling people affected by TB to take charge of their treatment. This is even more relevant now during the global COVID-19 pandemic, as many people face challenges in reaching clinical care and require home-based treatments. A recent survey by global civil society and TB affected communities on the impact of COVID-19 on TB found that up to 50% of survey respondents in Kenya reported difficulties finding transport to care facilities.
The inclusion of the Wisepill evriMED smart medication container in the GDF catalog marks a new chapter in the fight against TB. Until now, access to DATs had been limited, as large-scale procurement mechanisms for the products did not exist.
“For a long time now, the Stop TB Partnership is advocating for the need for innovative solutions to treat and cure people with TB. In these challenging times of the COVID-19 pandemic, I am even more proud to see health technology solutions seeing their way onto the GDF catalog to make sure there is no stopping in our progress against TB,” said Dr. Lucica. Ditiu, Executive Director, Stop TB Partnership.
In parallel, the ASCENT project is launching a Total Cost of Ownership tool, which can support countries to plan and budget for the adoption and scale-up of DAT use. The ASCENT project, which is funded by Unitaid and led by KNCV Tuberculosis Foundation, is the first to procure DATs through GDF; 5,000 Wisepill smart medication containers will support persons affected by TB in Ethiopia, the Philippines, South Africa, Tanzania, and Ukraine.
“Digital adherence technologies can provide complementary support to ensure patients take ownership of their care; it equally provides health care workers the opportunity for prioritization of individualized support,” said Dr. Mustapha Gidado, Executive Director, KNCV Tuberculosis Foundation.
“Innovative tools with the potential to simplify access to treatments for people affected by TB are crucial game changers. They can radically improve the way health workers deliver treatments, improve patients’ adherence, and ultimately save lives,” said Dr Philippe Duneton, Executive Director of Unitaid.
Lessons learned on the implementation, acceptability, feasibility, and effectiveness of different DATs in relation to treatment outcomes are forthcoming from the Stop TB Partnership’s TB REACH Wave 6 demonstration projects conducted in multiple countries and involving varied populations. As well as the Treatment Adherence Project, funded by the Bill & Melinda Gates Foundation.
“A critical enabler of the uptake of improved patient-centered digital adherence technologies is an easy and efficient way for country programs to procure the new tools. It's exciting to see the Global Drug Facility step forward to address this need and to provide this critical help to country programs,” Daniel Chin, Deputy Director, TB-HIV Program Strategy Team, Bill and Melinda Gates Foundation.