Brief news reports on Tuberculosis

Incident TB in one in three people starting antiretroviral therapy in Thailand

A study from Thailand has found that the incidence of tuberculosis was remarkably high among people with HIV during the first year on antiretroviral therapy, and thereafter, decreased significantly until reaching levels comparable to those in the Thai general population after ten years. The study, published in a recent issue of the Journal of the International AIDS Society, is important as it is most probably the first to report such data from a high TB/HIV burden country in Asia.

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TB: The disease that changed world history

Almost forgotten today, tuberculosis (TB) is still one of the deadliest infectious diseases in the world. In an interview with Coliquio, Ronald D. Gerste, MD, PhD, an ophthalmologist and historian, looked back on this disease's eventful history, which encompasses outstanding discoveries and catastrophic failures in diagnosis and treatment from the Middle Ages to the present day.

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U.S. Government funded research brings shorter TB treatment regimens to New York City

May 16, 2022 – We applaud the New York City Department of Health and Mental Hygiene (DoHMH) for its leadership as one of the first TB programs in the U.S. and globally to introduce a new four-month regimen for the treatment of drug-susceptible tuberculosis (TB). This new regimen represents a long-awaited breakthrough, offering a shorter alternative to the six-to-nine-month treatment in use since the 1980s. That the Department of Health and Mental Hygiene is moving forward to make this regimen available to patients will make treatment more tolerable for people living with TB. As TB survivor and activist Kate O’Brien of We Are TB and co-chair of the TB Roundtable put it, “TB treatment can be such a miserable experience, with all sorts of side effects and logistical complications. Shorter regimens offer patients welcome relief and I’m thrilled to see important government investments delivering better cures for TB.”

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Webinar: From evidence to action: Community-led monitoring for access to TB screening and diagnostic testing - materials now available online

On 4 May 2022, Treatment Action Group (TAG) and the Coalition of Women Living with HIV and AIDS (COWLHA) hosted a webinar on how community-led monitoring can be used to generate evidence for advocacy to improve the availability, accessibility, acceptability, and quality of TB screening and diagnostic services.

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Latent TB tied to increased diabetes risk

A study published in Diabetes Care suggested that people with latent TB infection are at increased risk of developing diabetes.

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Global Fund strategy to reduce deaths from AIDS, TB, and malaria still leaves TB behind

While TB kills more people each year than HIV/AIDS and malaria combined, more money is allocated to HIV and malaria than to TB in the new Global Fund strategy.

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India: TB activists start monthly meetings to resolve issues faced by TB patients

Mumbai: With the ongoing Covid-19 pandemic causing a setback for the country’s programme to eliminate tuberculosis (TB), non-government organisations (NGO), TB activists, survivors, and officers will hold a meeting every month to discuss the needs and challenges of its treatment in the country.

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TB laboratory manuals issued to support the implementation of WHO-recommended diagnostics

The World Health Organization and the Stop TB Partnership’s Global Laboratory Initiative working group release three new manuals to support the implementation of WHO-recommended TB diagnostics.

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A gene in tuberculosis bacteria is found essential for siderophore secretion and virulence

Lei Zhang, Ph.D., and Michael Niederweis, Ph.D., of the University of Alabama at Birmingham have made what they call “a major step” in understanding how Mycobacterium tuberculosis acquires iron from its human host — a process essential for the pathogenesis of this bacterium. Tuberculosis kills more than 1 million people each year, but without iron, M. tuberculosis cannot grow.

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Roche enters partnership with the Global Fund to support low- and middle-income countries in strengthening critical diagnostics infrastructure

-- Almost half of the world’s population has no or limited access to diagnostics

-- This situation is especially acute in low- and middle-income countries (LMICs) where diagnostics plays a critical role for treating and containing the spread of infectious diseases such as Tuberculosis (TB) and HIV

-- New partnership between Roche and the Global Fund supports low- and middle-income countries in broadening access to diagnostics, helping millions of previously undiagnosed people with TB and HIV get diagnosed and eventually treated

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