Caitlyn Stulpin

Study reveals association between CMV and latent TB

U.S. data revealed that cytomegalovirus was independently associated with latent tuberculosis infection, and both were associated with high levels of C-reactive protein, suggesting enhanced systemic inflammation, researchers reported.

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Nucleic acid amplification testing not performed in nearly half of confirmed US TB cases

The use of nucleic acid amplification testing for tuberculosis increased in the United States between 2011 and 2017, although nearly half of U.S. TB cases did not include one of the tests, according to a study.

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M. tuberculosis prosthetic joint infection rare but possible in some patients

Although prosthetic joint infections caused by Mycobacterium tuberculosis are rare, they may occur in immunocompromised patients or in people from regions where tuberculosis is endemic, researchers reported in a recent study.

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4-month TB regimen noninferior to 6-month regimen in people with HIV

A 4-month daily regimen of rifapentine and moxifloxacin was noninferior to the standard 6-month regimen for tuberculosis treatment among people with HIV enrolled in a phase 3 clinical trial, researchers reported at CROI.

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In shadow of COVID-19, TB vaccine research enters new era

In less than a year, scientists were able to develop several efficacious vaccines against COVID-19.

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Self-administered 3HP associated with high treatment completion for latent TB

Self-administered isoniazid-rifapentine taken once weekly — a regimen called 3HP — was associated with higher treatment completion rates for latent tuberculosis infection compared with daily rifampin, according to a study.

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Systematic, test-guided TB treatment result in similar outcomes

Systematic treatment for tuberculosis was not superior to test-guided treatment in reducing mortality or invasive bacterial disease among immunosuppressed adults with HIV, according to findings in The New England Journal of Medicine.

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Latent TB infection associated with very high alcohol use among people with HIV

Compared with medium-level alcohol use, very high use correlated with latent tuberculosis infection among adults with HIV in Uganda, according to a cross-sectional study in Clinical Infectious Diseases.

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TB in women in Ethiopia associated with HIV infection and aging

Tuberculosis among pregnant women in Ethiopia independently correlated with HIV infection and increasing age, which suggests that young women in the country are continuously exposed to, and infected with, contagious TB, according to findings in Clinical Infectious Diseases.

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TB recurrence increases by nearly ninefold between episodes 2 and 5

Rates of tuberculosis recurrence increased by almost ninefold between episode 2 and 5 regardless of HIV status, according to a study assessing recurrent tuberculosis in Cape Town, South Africa, over a 13-year period.

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