A shorter regimen containing rifapentine and moxifloxacin can cure TB in four months.

Have you heard?? ACTG 5279: One-month TB prophylaxis as effective as nine-month regimen for people living with HIV

January 10, 2018 – The Tuberculosis Trials Consortium (TBTC) is a global leader in research and development for better tools to prevent, diagnose, and treat tuberculosis (TB). Housed within the U.S. Centers for Disease Control and Prevention (CDC), the TBTC conducts clinical research of high public health relevance and is key to strengthening domestic and global campaigns to eliminate TB. TBTC studies have produced several notable breakthroughs, including a shorter regimen for preventing TB (3HP) using isoniazid and rifapentine. The Community Research Advisors Group (CRAG) produced this briefing document to raise awareness of the TBTC’s legacy of accomplishments; highlight major advances in TB care resulting from TBTC studies; and make the case for increasing funding for TB research at CDC in line with the goals of the U.S. National Action Plan for Combatting Multidrug-Resistant Tuberculosis.

The Community Research Advisors Group urges Sanofi to submit a bid for rifapentine to be included in the Stop TB Partnership's Global Drug Facility catalogue.

Meeting description:

Community groups sent public comments in support of the addition of rifapentine, delamanid, bedaquiline and linezolid to the WHO Model List of Essential Medicines.

An open letter requests that The Union take steps to retire the use of stigmatizing and criminalizing terminology from the papers published in its journals and the abstracts submitted to its conferences.

The document is designed to facilitate community reviews of clinical trials protocols and to ensure community participation in protocol development.

Several community groups express concerns regarding the STREAM stage II trial design for bedaquiline approval.

Community groups express concern for AstraZeneca's departure from tuberculosis and urge the company to ensure continued investment in the field.